Gastric acid-inhibiting drugs, for example, often against heartburn for use, could increase the risk for various allergies. The suggest-to-date prescription data from Austria. It was found that an acid blocker-regulation very often also anti-Allergy regulations are followed.
Researchers suspect for some time that drugs that affect the acid composition in the stomach, have unwanted effects on the immune system. A new study by the Medical University of Vienna supported this suspicion. Patients received a physician-prescribed gastric protection, such as proton pump inhibitors (PPI), a H2-Blocker, sucralfate or Prostaglandin E2, it was a risk, to get in the following years, an anti-allergic agent, on average, twice as high as in patients who take other medications such as blood pressure or lipid-lowering agents were prescribed. The regulation of six daily doses of acid blockers per year was enough to increase the risk. The more acid blocker doses were prescribed, the more likely it is also an antihistamines, followed by the prescription, the researchers report currently in "Nature Communications".
Women had a higher risk than men, and age also played a big role: for example, the Rate for the Under-20-Year-old to a 47 percent increase in the 60-Year-old was even to 520 percent. Seniors had to take to a protective Acid-regulation more than five times as often, an anti-allergic drug, as to be expected, was normal. The regulation data show, however, against what kind of Allergy the antihistamines or specific immune therapies have been prescribed.
For the study, researchers analyzed by Professor Dr. Erika Jensen-Jarolim, the prescription data of more than eight million Austrians, between 2009 and 2013. This corresponds to approximately 97 percent of the population. The study show no causal connection, yet the findings are a further indication, acid blocker like a PPI is not uncritically take over a prolonged period. The Jensen-Jarolim: " says;The so-called ‚Magenschoner‘ you should not use any longer than necessary. Prevent the digestion of protein, change the Microbiome in the gastrointestinal tract and increase the risk for allergic reactions. Once you have completed your medically prescribed task, should you take off you quickly." In 2013 alone, more than 1.5 million people in Austria, a PPI prescription. The are 17.4 percent of the total population.