Can medical marijuana help treat intractable epilepsy?

A new British Journal of Clinical Pharmacology review examines the potential of medicinal cannabis—or medical marijuana—for helping patients with intractable epilepsy, in which seizures fail to come under control with standard anticonvulsant treatment.

The authors note that cannabidiol—the most researched compound of cannabis—may have modest efficacy and be appropriate for children with severe epilepsy, but attention must be paid to potential side effects and drug interactions. There is no evidence to guide physicians in ranking cannabidiol among current antiepileptic drugs, and it will be important to continue studying its potential through rigorous clinical trials.

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